Carrie Coon (Callie Spengler), Finn Wolfhard (Trevor Spengler), Mckenna Grace (Phoebe Spengler), Paul Rudd (Gary Grooberson), Logan Kim (Podcast), Celeste O'Connor (Lucky), Bill Murray (Dr. Peter Venkman) more..., Dan Aykroyd (Dr. Raymond Stantz), Ernie Hudson (Winston Zeddemore), Annie Potts (Janine Melnitz), Sigourney Weaver (Dana Barrett), Bokeem Woodbine (Sheriff Domingo), Tracy Letts (Jack (uncredited)), J.K. Simmons (Ivo Shandor), Josh Gad (Muncher (voice)), Bob Gunton (The Ghost Farmer), Billy Bryk (Zahk), Sydney Mae Diaz (Swayze), Shawn Seward (Skittles), Hannah Duke (Reseda), Paulina Jewel Alexis (Bunny), Marlon Kazadi (Thick Neck), Chiara Petersen (Burner Girl), Danielle Kennedy (Roller Granny), Artoun Nazareth (Rufus), Crystal Roseborough (Crystal), Dusan Rokvic (Landlord), Emma Portner (Spirit of Gozer), Stella Aykroyd (Deputy Medjuck), Kim Faires (Waitress), Shohreh Aghdashloo (Gozer (voice)), Olivia Wilde (Gozer the Gozerian (uncredited)), Harold Ramis (Dr. Egon Spengler (archive footage)), Oliver Cooper (Elton (uncredited)), CJ Collard (Diner Patron (uncredited)), Bud Klasky (Sheriff / Restaurant (uncredited)), Faith Louissaint (Diner Counter Staff (uncredited)), Daniel D'Angelo Sparks (Walmart Customer (uncredited))

Danny Glicker (Costume Design), Ivan Reitman (Producer), Jason Reitman (Writer), Eric Steelberg (Director of Photography), Dana E. Glauberman (Editor), Guy Bews (Stunt Coordinator), Gil Kenan (Writer) more..., Steven Morrow (Sound Mixer), James Isaacson (Props), C.J. Hannis (Cast Driver), Ashley MacMillan (Props), Nathan Orloff (Editor), Dan Aykroyd (Original Film Writer), Harold Ramis (Original Film Writer), Rob Simonsen (Original Music Composer), John Papsidera (Casting), François Audouy (Production Design), Scott Meehan (Art Direction), Tom Reta (Art Direction), Chris Terhune (Sound Designer), Scott Sanders (Sound Designer), Bill Ives (Art Direction), Paul Healy (Set Decoration), Michael Lemon (VFX Artist), Peter Stratford (Set Designer), Perry Robertson (Supervising Sound Editor), Will Files (Supervising Sound Editor), Will Files (Sound Re-Recording Mixer), Mark Paterson (Sound Re-Recording Mixer), Sheena Duggal (Visual Effects Supervisor), Joanne Jacobsen (Makeup Department Head), Joel Tobman (Assistant Art Director), Kevin Zimmerman (Sound Editor), Ed Symon (Set Designer), Sarah Moussaif (Visual Effects Producer), Chris LeDoux (Visual Effects), Tracey Graham (Set Costumer), Sid Jayakar (Visual Effects Supervisor), Doug Spilatro (VFX Artist), Katrina Sainz (Assistant Art Director) and others.