William Shatner (Admiral James T. Kirk), Leonard Nimoy (Captain Spock), DeForest Kelley (Dr. Leonard 'Bones' McCoy), James Doohan (Captain Montgomery 'Scotty' Scott), George Takei (Cmdr. Hikaru Sulu), Walter Koenig (Cmdr. Pavel Chekov), Nichelle Nichols (Cmdr. Uhura) more..., Mark Lenard (Sarek), Jane Wyatt (Amanda), Majel Barrett (Commander Chapel), Robert Ellenstein (Federation Council President), John Schuck (Klingon Ambassador), Brock Peters (Admiral Cartwright), Robin Curtis (Lt. Saavik), Catherine Hicks (Gillian), Michael Snyder (Starfleet Communications Officer), Michael Berryman (Starfleet Display Officer), Mike Brislane (Saratoga Science Officer), Grace Lee Whitney (Commander Rand), Jane Wiedlin (Alien Communications Officer), Vijay Amritraj (Starship Captain), Nick Ramus (Saratoga Helmsman), Thaddeus Golas (Controller #1), Marty Pistone (Controller #2), Scott Devenney (Bob Briggs), Viola Kates Stimpson (Lady in Tour), Phil Rubenstein (1st Garbageman), John Miranda (2nd Garbageman), Joe Knowland (Antique Store Owner), Bob Sarlatte (Waiter), Everett Lee (Cafe Owner), Richard Harder (Joe), Alex Henteloff (Nichols), Tony Edwards (Pilot), Eve Smith (Elderly Patient), Tom Mustin (Intern #1), Greg Karas (Intern #2), Raymond Singer (Young Doctor), David Ellenstein (Doctor #1), Judy Levitt (Doctor #2) and others.

Harve Bennett (Producer), Steve Meerson (Screenplay), Peter Krikes (Screenplay), Harve Bennett (Screenplay), Nicholas Meyer (Screenplay), Donald Peterman (Director of Photography), Joe Aubel (Art Direction) more..., Peter Landsdown Smith (Art Direction), John M. Dwyer (Set Decoration), Robert Fletcher (Costume Design), Leonard Rosenman (Original Music Composer), Amanda Mackey (Casting), Jack T. Collis (Production Design), Peter Landsdown Smith (Production Design), Peter E. Berger (Editor), Kirk R. Thatcher (Associate Producer), Douglas Freeman (Construction Coordinator), Ken Ralston (Visual Effects Supervisor), Mel Efros (Unit Production Manager), Mark Mangini (Sound Effects), Armen Ksajikian (Musician), Eddie Hice (Stunts), Leonard Nimoy (Story), Harve Bennett (Story), Nilo Rodis-Jamero (Assistant Art Director), Ralph Winter (Executive Producer), Jeff Dawn (Makeup Artist), Rick Stratton (Makeup Artist), R.A. Rondell (Stunt Coordinator), Alan Howarth (Sound Effects), Brooke Breton (Associate Producer), Frank Capra III (Second Assistant Director), Pat Kehoe (First Assistant Director), David J. Hudson (Sound Re-Recording Mixer), Mel Metcalfe (Sound Re-Recording Mixer), Terry Porter (Sound Re-Recording Mixer), Carol A. O'Connell (Hairstylist), Cliff Fleming (Stunts), Michael Lantieri (Special Effects), Spike Silver (Stunts) and others.