Billy Crudup (Russell Hammond), Frances McDormand (Elaine Miller), Kate Hudson (Penny Lane), Jason Lee (Jeff Bebe), Patrick Fugit (William Miller), Zooey Deschanel (Anita Miller), Michael Angarano (Young William) more..., Anna Paquin (Polexia Aphrodisia), Fairuza Balk (Sapphire), Noah Taylor (Dick Roswell), John Fedevich (Ed Vallencourt), Mark Kozelek (Larry Fellows), Philip Seymour Hoffman (Lester Bangs), Liz Stauber (Leslie), Jimmy Fallon (Dennis Hope), Olivia Rosewood (Beth from Denver), Bijou Phillips (Estrella Starr), Alice Marie Crowe (Mrs. Deegan), J.J. Cohen (Roadie Scully), Gary Kohn (Roadie Gregg), Ray Porter (Roadie Mick), Mark Pellington (Freddy), Eion Bailey (Jann Wenner), Terry Chen (Ben Fong-Torres), Rainn Wilson (David Felton), Erin Foley (Alison the Fact Checker), Jesse Caron (Darryl), Charles Walker (Principal), Jay Baruchel (Vic Munoz), Pauley Perrette (Alice Wisdom), Peter Frampton (Reg), Zack Ward (The Legendary Red Dog), Mitch Hedberg (Eagles Road Manager), Devin Corey (The Who Road Manager), Pete Droge (Hyatt Singer), Elaine Summers (Hyatt Singer), Eric Stonestreet (Sheldon the Desk Clerk), Marc Maron (Angry Promoter), Shane Willard (Ticket Scalper), Chris McElprang (Aaron Amedori) and others.

Clay A. Griffith (Art Direction), John Toll (Director of Photography), Joe Hutshing (Editor), Ian Bryce (Producer), Robert Greenfield (Set Decoration), Betsy Heimann (Costume Design), Cameron Crowe (Producer) more..., Lisa Stewart (Producer), Scott M. Martin (Producer), Nancy Wilson (Original Music Composer), Saar Klein (Editor), Gail Levin (Casting), Steven P. Saeta (Production Manager), David Kelley (Second Assistant Director), Charles Croughwell (Stunt Coordinator), Jerry Ziesmer (Associate Producer), Jerry Ziesmer (First Assistant Director), John Frazier (Special Effects Supervisor), Steven P. Saeta (Associate Producer), Marty P. Ewing (Production Manager), Marty P. Ewing (Associate Producer), Virginia Randolph-Weaver (Art Direction), Michael Dennison (Costume Supervisor), Paul Massey (Sound Re-Recording Mixer), Laurie Webb (Second Second Assistant Director), Don Coufal (Boom Operator), Charisse Cardenas (Set Designer), Neal Preston (Still Photographer), Lois Burwell (Makeup Department Head), Jonny Pray (Costumer), Michael Germain (Key Makeup Artist), Doug Hemphill (Sound Re-Recording Mixer), Rick Kline (Sound Re-Recording Mixer), David H. Allen (Property Master), Patia Prouty (Costumer), Eric Rosenberg (Assistant Art Director), Mindy R. Toback (Set Designer), Chris Haarhoff (Camera Operator), Chris Napolitano (Rigging Gaffer), Kathryn Blondell (Hair Department Head) and others.