Margot Robbie (Harleen Quinzel / Harley Quinn), Ewan McGregor (Roman Sionis / Black Mask), Mary Elizabeth Winstead (Helena Bertinelli / Huntress), Jurnee Smollett-Bell (Dinah Lance / Black Canary), Rosie Perez (Detective Renee Montoya), Chris Messina (Victor Zsasz), Ella Jay Basco (Cassandra Cain) more..., Ali Wong (Ellen Yee), Matthew Willig (Happy), Dana Lee (Doc), Steven Williams (Patrick Erickson), Robert Catrini (Stefano Galante), Daniel Bernhardt (Sionis' Chauffeur), François Chau (Mr. Keo), Miyuki Matsunaga (Mrs. Keo), Anna Mikami (Miss Keo), Paul Lasa (Franco Bertinelli), Charlene Amoia (Maria Bertinelli), Ella Mika (Young Helena Bertinelli), Derek Wilson (Tim Evans), Bojana Novaković (Erika), Andy Hoff (Erika's Date), Bruno Oliver (Sal), Michael Masini (Officer Dargo), Judy Kain (Bespectacled Secretary), David Bianchi (Henchman), Rj Wayne (Tough Guy), Eddie Alfano (Helena's Bodyguard), Simon Rhee (Cell Guard)

K.K. Barrett (Production Design), K.K. Barrett (Production Designer), Matthew Libatique (Director of Photography), Jay Cassidy (Editor), David Ayer (Executive Producer), Walter Hamada (Executive Producer), Jonathan Eusebio (Stunt Coordinator) more..., Kelley Smith-Wait (Executive In Charge Of Production), Mark DeSimone (ADR Mixer), Paula Fairfield (Sound Designer), Hans Ritter (Executive Producer), Brittany Petros (Location Manager), Geoff Johns (Executive Producer), Margot Robbie (Producer), Claudette Barius (Still Photographer), Daniel Pemberton (Original Music Composer), Rich Delia (Casting), Kasra Farahani (Supervising Art Director), Luke Gibleon (Sound Effects Editor), Erin Benach (Costume Designer), Brandon Proctor (Sound Re-Recording Mixer), Craig Dollinger (Boom Operator), Michael W. Mitchell (Sound Effects Editor), Rich Romig (Set Designer), Evan Schiff (Editor), Phil Barrie (Sound Effects Editor), Darren Maynard (Sound Effects Editor), Jon Valera (Fight Choreographer), Annemarie Griggs (Visual Effects Producer), Christina Hodson (Screenplay), Katy Wood (Supervising Sound Editor), Amy Lynn Umezu (Storyboard Artist), Steven Morrow (Sound Mixer), Mark Hawker (Special Effects Supervisor), Bryan Unkeless (Producer), Julien Pougnier (Art Direction), Kenneth Au (Visual Effects Supervisor), Sue Kroll (Producer), Julia Saeri Lee (Costume Assistant), Bryan Mendoza (Utility Sound) and others.