Robert De Niro (Sam 'Ace' Rothstein), Sharon Stone (Ginger McKenna), Joe Pesci (Nicky Santoro), James Woods (Lester Diamond), Don Rickles (Billy Sherbert), Alan King (Andy Stone), Kevin Pollak (Phillip Green) more..., Pasquale Cajano (Remo Gaggi), L. Q. Jones (Pat Webb), Dick Smothers (Senator), Frank Vincent (Frank Marino), Oscar Goodman (Oscar Goodman), Richard Riehle (Charlie Clark), Catherine Scorsese (Piscano's Mother), Vinny Vella (Artie Piscano), Nobu Matsuhisa (Ichikawa), Erika von Tagen (Amy), Nick Mazzola (Black Jack-Groupier), David Rose (David), John Bloom (Don Ward), Joseph Rigano (Vincent Borelli), Philip Suriano (Dominick Santoro), Melissa Prophet (Jennifer Santoro), Bill Allison (John Nance), Joe La Due (Signaller), Joseph P. Reidy (Winner), Craig Vincent (Cowboy), Carl Ciarfalio (Tony Dogs), Gene Ruffini (Vinny Forlano), Dominick Grieco (Americo Capelli), Clem Caserta (Sal Fusco), Daniel P. Conte (Doctor Dan), Joey DePinto (Stabbed Gambler), Jack Orend (Baker), Paul Herman (Gambler in Phone Booth), Jed Mills (Jack Hardy), Claudia Haro (Trudy), Ffolliott Le Coque (Anna Scott), John Manca (Wiseguy Eddie), Ronald Maccone (Wiseguy Jerry) and others.

Robert Richardson (Director of Photography), Jack G. Taylor Jr. (Art Direction), Rick Simpson (Set Decoration), Martin Scorsese (Screenplay), Eugene Gearty (Sound Editor), Ellen Lewis (Casting), Dante Ferretti (Production Design) more..., Georgia Kacandes (Unit Production Manager), Thelma Schoonmaker (Editor), Dan Korintus (Dialogue Editor), David Boulton (ADR Engineer), Rita Ryack (Costume Design), Nicholas Pileggi (Screenplay), Nicholas Pileggi (Novel), Barbara De Fina (Producer), Joseph P. Reidy (Associate Producer), Skip Lievsay (Supervising Sound Editor), Bradley M. Goodman (Post Production Supervisor), James Y. Kwei (Associate Editor), Mike Higelmire (Leadman), Pasquale Buba (Additional Editor), Ilona Herman (Hairstylist), Phillip V. Caruso (Still Photographer), Maggie Morgan (Assistant Costume Designer), Terry Erickson (Special Effects), John Dunn (Costume Design), Kathleen M. Courtney (Production Coordinator), Kam Chan (Foley Editor), Marko A. Costanzo (Foley Artist), Chris Fielder (Assistant Sound Editor), Robbie Robertson (Music Consultant), Scott Harris (Second Assistant Director), Daniel W. Barringer (Stunt Coordinator), Jo-Anne Smith-Ojeil (Key Makeup Artist), Ian Kincaid (Gaffer), Elaine Bass (Title Designer), Reilly Steele (Additional Sound Re-Recording Mixer), Paul J. Lombardi (Special Effects Coordinator), Nancy McArdle (Costume Supervisor), Michael J. Burmeister (Location Manager) and others.