Robert De Niro (Sam 'Ace' Rothstein), Sharon Stone (Ginger McKenna), Joe Pesci (Nicky Santoro), James Woods (Lester Diamond), Don Rickles (Billy Sherbert), Alan King (Andy Stone), Kevin Pollak (Phillip Green) more..., L.Q. Jones (Pat Webb), Dick Smothers (Senator), Frank Vincent (Frank Marino), John Bloom (Don Ward), Pasquale Cajano (Remo Gaggi), Melissa Prophet (Jennifer Santoro), Bill Allison (John Nance), Vinny Vella (Artie Piscano), Oscar Goodman (Himself), Catherine Scorsese (Piscano's Mother), Philip Suriano (Dominick Santoro), Erika von Tagen (Older Amy), Frankie Avalon (Himself), Steve Allen (Himself), Jayne Meadows (Herself), Jerry Vale (Himself), Joseph Rigano (Vincent Borelli), Gene Ruffini (Vinny Forlano), Dominick Grieco (Americo Capelli), Peter Conti (Arthur Capp), Cathy Scorsese (Piscano's Daughter), Steve Vignari (Beeper), Paul Herman (Gambler in Phone Booth), Joey DePinto (Stabbed Gambler), Millicent Sheridan (Senator's Hooker), Nobu Matsuhisa (Ichikawa), Frankie J. Allison (Craps Dealer), Anthony Russell (Bookie), John Manca (Wiseguy Eddie), Ronald Maccone (Wiseguy Jerry), Joseph P. Reidy (Winner), Joe La Due (Signaller), Stuart Nisbet (LA Banker) and others.

Robert Richardson (Director of Photography), Jack G. Taylor Jr. (Art Direction), Rick Simpson (Set Decoration), Martin Scorsese (Screenplay), Eugene Gearty (Sound Editor), Ellen Lewis (Casting), Dante Ferretti (Production Design) more..., Georgia Kacandes (Unit Production Manager), Thelma Schoonmaker (Editor), Dan Korintus (Dialogue Editor), David Boulton (ADR Engineer), Rita Ryack (Costume Design), Nicholas Pileggi (Screenplay), Nicholas Pileggi (Novel), Barbara De Fina (Producer), Joseph P. Reidy (Associate Producer), Skip Lievsay (Supervising Sound Editor), Bradley M. Goodman (Post Production Supervisor), James Y. Kwei (Associate Editor), Mike Higelmire (Leadman), Pasquale Buba (Additional Editor), Ilona Herman (Hairstylist), Phillip V. Caruso (Still Photographer), Maggie Morgan (Assistant Costume Designer), Terry Erickson (Special Effects), John Dunn (Costume Design), Kathleen M. Courtney (Production Coordinator), Kam Chan (Foley Editor), Marko Costanzo (Foley Artist), Chris Fielder (Assistant Sound Editor), Robbie Robertson (Music Consultant), Scott Harris (Second Assistant Director), Daniel W. Barringer (Stunt Coordinator), Jo-Anne Smith-Ojeil (Key Makeup Artist), Ian Kincaid (Gaffer), Elaine Bass (Title Designer), Reilly Steele (Additional Sound Re-Recording Mixer), Paul J. Lombardi (Special Effects Coordinator), Nancy McArdle (Costume Supervisor), Michael J. Burmeister (Location Manager) and others.