Idris Elba (Dr. Ben Bass), Kate Winslet (Alex Martin), Dermot Mulroney (Mark Robertson), Beau Bridges (Walter), Linda Sorensen (Pamela), Tintswalo Khumbuza (Sarah Bass), Dania Nassar (Mrs. Qabbani) more..., Vincent Gale (Airline Customer Service), Marci T. House (Airline Representative), Lee Majdoub (Translator), Andres Joseph (Dinner Guest), Nancy Sivak (Nurse), Bethany Brown (New York Waiter), Orval Roberts (Logging Truck Driver), Lucia Walters (London Doctor (uncredited)), Natasha Burnett (London Nurse (uncredited)), Nadeen Lightbody (Partygoer (uncredited)), Adam Lolacher (Joel (uncredited))

Lee Percy (Editor), Chris Weitz (Screenplay), Renee Ehrlich Kalfus (Costume Design), James Steuart (Supervising Art Director), Jenno Topping (Producer), Becki Cross Trujillo (Executive Producer), Becki Cross Trujillo (Unit Production Manager) more..., Cheryl Marion (Art Direction), Jon Lavender (Boom Operator), Tom Blacklock (Special Effects), Mandy Walker (Director of Photography), Susan Hegarty (Dialect Coach), J. Mills Goodloe (Writer), Peter Chernin (Producer), Dylan Clark (Producer), Philip Needs (Second Assistant Director), David Ready (Producer), Paul Barry (First Assistant Director), Robert Edwards (ADR Mixer), Kimberly French (Still Photographer), Megan Tanner (Makeup Artist), Sandra-Ken Freeman (Casting), Hans Bjerno (Aerial Director of Photography), Sian Grigg (Makeup Artist), Braden Haggerty (Camera Operator), Shannon Gottlieb (Set Decoration), Thierry Tanguy (Unit Production Manager), Angela O'Sullivan (Assistant Art Director), Paul Benjamin (Special Effects Supervisor), Cara E. Anderson (Special Effects), Christian Madera (Visual Effects Editor), Korey J. Cauchon (Visual Effects Producer), Fred Berger (Executive Producer), Johnny Gidcomb (ADR Voice Casting), Tony Beck (Leadman), Amira Diab (Associate Producer), Charles Martin (Novel), Tim Macarthur (Assistant Director), Amanda Petura (Third Assistant Director), Jeremiah Slovarp (Recording Supervision) and others.