Milla Jovovich (Alice), Wentworth Miller (Chris Redfield), Ali Larter (Claire Redfield), Kim Coates (Bennett), Kacey Clarke (Crystal), Shawn Roberts (Albert Wesker), Sergio Peris-Mencheta (Angel) more..., Boris Kodjoe (Luther West), Sienna Guillory (Jill Valentine), Spencer Locke (K-Mart), Norman Yeung (Kim Yong), Ray Olubowale (Axeman), Christopher Kano (Sniper), Tatsuya Goke (Sniper), Fulvio Cecere (Wendell), Nobuya Shimamoto (Technician #1), Peter Kosaka (Duty Officer), Denis Akiyama (Captain Hotaka), Kenta William Tomeoki (Technician #2), Shin Kawai (Umbrella Sergeant), Mika Nakashima (J Pop Girl), Takato Yamashita (Business Man), Hiromi Okuyama (Kogel Girl Undead)

Paul W.S. Anderson (Screenplay), Paul W.S. Anderson (Producer), Jeremy Bolt (Producer), Robert Kulzer (Producer), Bernd Eichinger (Producer), Niven Howie (Editor), Samuel Hadida (Producer) more..., Don Carmody (Producer), Stephen Barden (Supervising Sound Editor), Denise Cronenberg (Costume Design), Burton J. LeBlanc (Assistant Makeup Artist), Arvinder Grewal (Production Design), Martin Moszkowicz (Executive Producer), David Franco (Second Unit Director of Photography), Glen MacPherson (Director of Photography), Robin D. Cook (Casting), Brandt Gordon (Art Direction), Victor Hadida (Executive Producer), Richard Redlefsen (Makeup Effects), Igor Meglic (Second Unit Director of Photography), Gregor Hutchison (Post Production Supervisor), Tracey McLean (Matte Painter), Carolyn 'Cal' Loucks (Set Decoration), Andrew Stirk (Sound Re-Recording Mixer), Justin Smith (Visual Effects Production Assistant), Vladislav Fyodorov (Set Designer), Christina Smith (Makeup Artist), Dennis Berardi (Visual Effects Supervisor), Coll Anderson (Sound Designer), Brian Kobo (Production Coordinator), Al Vrkljan (Armorer), Jason Detheridge (Prosthetic Makeup Artist), Ronald Gilbert (Production Manager), Hiroyuki Kobayashi (Producer), Rocky Faulkner (Makeup Effects), Steve Baine (Foley Artist), Azalia Snail (Costume Design), Leslie A. Sebert (Makeup Department Head), Wojciech Zielinski (Visual Effects Supervisor), Jill Purdy (Dialogue Editor) and others.