George Clooney (Augustine Lofthouse), Felicity Jones (Sully), David Oyelowo (Adewole), Caoilinn Springall (Iris), Kyle Chandler (Mitchell), Demián Bichir (Sanchez), Tiffany Boone (Maya) more..., Sophie Rundle (Jean), Ethan Peck (Young Augustine), Tim Russ (Mason Mosley), Miriam Shor (Mitchell's Wife), Lilja Nótt Þórarinsdóttir (Frantic Woman - Katherine), Hanna María Karlsdóttir (Older Woman), Atli Óskar Fjalarsson (Soldier), Edan Hayhurst (Mitchell Son 1), Jamie Schneider (Mitchell Son 2), Eysis Clacken (Rachel), Sam Bond (Father in Plane), Tia Bannon (Jasmine), Natasha Jenssen (Speech Guest (uncredited)), Bharat Mistri (Speech Guest (uncredited)), Jill Buchanan (Benefactor (uncredited)), Kishore Bhatt (Speech Guest (uncredited)), Gsus Lopez (Extra (uncredited)), Paul Riddell (Philanthropist (uncredited)), Grant Crookes (Scientific Beneficiary (uncredited))

George Clooney (Producer), Stephen Mirrione (Editor), Alexandre Desplat (Original Music Composer), James D. Bissell (Production Design), Barbara A. Hall (Executive Producer), Helen Jarvis (Supervising Art Director), Grant Heslov (Producer) more..., Martin Ruhe (Director of Photography), Keith Redmon (Producer), Mark L. Smith (Screenplay), John Bush (Set Decoration), Rachel Tenner (Casting), Jenny Eagan (Costume Design), Lee Grumett (First Assistant Director), Greg Baxter (Executive Producer), Sam Breckman (Unit Production Manager), Bard Dorros (Producer), Leifur B. Dagfinnsson (Line Producer), Lucy Rands (Casting), Nic Pallace (Art Direction), Tim Browning (Art Direction), Jonathan Opgenhaffen (Art Direction), Claire Fleming (Art Direction), Maudie Andrews (Set Decoration), Lily Brooks-Dalton (Book), Todd Shuster (Executive Producer), James J. Reid (Second Assistant Director), Cliff Roberts (Producer), Magnus Thulin (Line Producer),