Jonathan Majors (Nat Love), Idris Elba (Rufus Buck), Regina King (Trudy Smith), Zazie Beetz (Stagecoach Mary), Delroy Lindo (Bass Reeves), Danielle Deadwyler (Cuffee), Lakeith Stanfield (Cherokee Bill) more..., Edi Gathegi (Bill Pickett), RJ Cyler (Jim Beckwourth), Deon Cole (Wiley Escoe), Julio Cedillo (Jesus Cortez), Damon Wayans Jr. (Monroe Grimes), Woody McClain (Clyde Grimes), Jacobi Howard (Angel), Tait Fletcher (Biggest Man on the Train), Dylan Kenin (General Abbott), Andria B Langston (Bank Teller), Ernest Marsh (Cowboy), Chanel Mack (Lady of the Night), Tracy Obonna (Lady of the Night), Howard Ferguson Jr. (Prison Lieutenant), Bonita King (Bank Patron), Mickey Dolan (Jake Abbott), Michael Beach (Mr. Love), DeWanda Wise (Eleanor Love), Chase W. Dillon (Young Nat), Marissa Freeman (Lady of the Night), Sadiqua Bynum (Eleanor Love), Zacciah Hanson (Prisoner Guard), DyNiesha Lysette Whitfield (Lady of the Night), David Hight (Train Server), Stephanie Hill (Train Passenger), Vic Browder (Prison Guard), Ivan Lee Holmes (Shopkeeper), Michael E. Stogner (Maysville Citizen), Angie Jenkins (Lady of the Night), Steve Corona (Maysville Bank Manager), Peyton Jackson (Woody), J. Nathan Simmons (Maysville Citizen), Terrence Clowe (Zeke) and others.

Lawrence Bender (Producer), James Lassiter (Producer), Boaz Yakin (Screenplay), Jay-Z (Producer), Jeymes Samuel (Screenplay), Jeymes Samuel (Producer), Victoria Thomas (Casting) more..., Jay Hart (Set Decoration), G. Mac Brown (Executive Producer), Martin Whist (Production Design), Mihai Malaimare Jr. (Director of Photography), Jay-Z (Executive Producer), Cynthia La Jeunesse (Set Decoration), Gregory S. Hooper (Art Direction), Antoinette Messam (Costume Design), Matthew Gatlin (Art Direction), Richard King (Sound Designer), Richard King (Supervising Sound Editor), Jon Shroyer (Makeup Artist), Chris F. Moore (Visual Effects), Shutchai Tym Buacharern (Makeup Department Head), Randy Torres (Sound Editor), Kris Wood (Visual Effects Supervisor), Robert Kato DeStefan (Makeup Artist), Nysh Yellowhorse (Makeup Artist), Ron Bartlett (Sound Re-Recording Mixer), Greg Papalia (Set Designer), Roland N. Thai (Sound Effects Editor), Phil Shirey (Leadman), David Bach (Dialogue Editor), Douglas Shamburger (Boom Operator), G. A. Aguilar (Second Unit Director), Richard Bucher (Stunt Coordinator), Brian Brown (Utility Stunts), Roberta Marquez Seret (Art Department Coordinator), Claudia Sarbu (Costume Supervisor), Lorrie Campbell (Set Designer), Clint Bennett (Music Editor), Anthony Ortiz (Sound Mixer), Doug Hemphill (Sound Re-Recording Mixer) and others.