Virginie Efira (Sister Benedetta Carlini), Charlotte Rampling (Sister Felicita), Daphné Patakia (Bartolomea), Lambert Wilson (Nuncio), Olivier Rabourdin (Alfonso Cecchi), Louise Chevillotte (Sister Christina), Hervé Pierre (Paolo Ricordati) more..., Clotilde Courau (Midea Carlini), David Clavel (Giuliano Carlini), Guilaine Londez (Sister Jacopa), Gaëlle Jeantet (Sister Petra), Justine Bachelet (Sister Juliana), Lauriane Riquet (Sister Roasanna), Eléna Plonka (Young Benedetta), Héloïse Bresc (Christina enfant), Jonathan Couzinié (Jésus-Christ), Vinciane Millereau (Doctor), Jérôme Chappatte (Secretary), Ewan Ribard (Executioner), Nicolas Béguinot (Writer), Satya Dusaugey (Mercenary Dragon), Nicolas Gaspar (Captain of the Mercenaries), Benjamin Penemaria (Captain of Soldiers), Antoine Lelandais (Lieutenant), Frédéric Sauzay (Shepherd), Sophie Breyer (Novice), Célia Kaci (Young Novice), Alexia Chardard (Sister Giulia), Sébastien Chabane (Passerby), Boris Gillot (Merchant), Léa Lopez (Teenager from Pescia #1), Olga Milshtein (Teenager from Pescia #2), Pascal Le Corre (Flagellant), Raphaël Potier (Plague Victim), Philippe Saunier (Resident of Pescia), Fabrice Cals (City Resident), Quentin D'Hainaut (Villager (uncredited)), Mirko Filippi (Flagellante), Franco Filippi (Popolano)

Paul Verhoeven (Screenplay), Saïd Ben Saïd (Producer), Jérôme Seydoux (Producer), Job ter Burg (Editor), David Birke (Screenplay), Michel Merkt (Producer), Jeanne Lapoirie (Director of Photography) more..., Anne Dudley (Original Music Composer), Jean-Paul Mugel (Sound Mixer), Katia Wyszkop (Production Design), Pierre-Jean Larroque (Costume Design), Eric Bourges (Art Direction), Stéphane Batut (Casting), Katia Boutin (Dialogue Editor), Katia Boutin (ADR Supervisor), Philippe Penot (Foley Artist), Cyril Holtz (Sound Re-Recording Mixer), Damien Lazzerini (Sound Re-Recording Mixer), Florian Penot (Assistant Foley Artist), Damien Luquet (Boom Operator), Alexis Place (Sound Supervisor), Charles de Ville (Sound Editor), Margot Saada (ADR Editor), Jules Laurin (Foley Editor), Antoine Citrinot (Assistant Sound Editor), Conchita Airoldi (Executive Producer), Frans van Gestel (Co-Producer), Alain Carsoux (Visual Effects Director), Teun Hilte (Co-Producer), Job ter Burg (Associate Producer), Arnold Heslenfeld (Co-Producer), Guillaume Le Gouez (Visual Effects Supervisor), Laurette Schillings (Co-Producer), Kevin Chneiweiss (Associate Producer), Marion Frelat (Visual Effects Coordinator), Fabrice Delville (Co-Producer), Christophe Toulemonde (Co-Producer), Patrick Vandenbosch (Co-Producer), Kateryna Merkt (Associate Producer), Ayelen Camiña (Visual Effects Coordinator) and others.