Josh Brolin (Llewelyn Moss), Javier Bardem (Anton Chigurh), Tommy Lee Jones (Ed Tom Bell), Kelly Macdonald (Carla Jean Moss), Woody Harrelson (Carson Wells), Garret Dillahunt (Wendell), Tess Harper (Loretta Bell) more..., Barry Corbin (Ellis), Stephen Root (Man who hires Wells), Rodger Boyce (El Paso Sheriff), Beth Grant (Carla Jean's Mother), Ana Reeder (Poolside Woman), Kit Gwin (Sheriff Bell's Secretary), Zach Hopkins (Strangled Deputy), Chip Love (Man in Ford), Eduardo Antonio Garcia ("Agua" Man), Gene Jones (Gas Station Proprietor), Myk Watford ("Managerial" Victim), Boots Southerland ("Managerial" Victim), Kathy Lamkin (Desert Aire Manager), Johnnie Hector (Cabbie at Bus Station), Margaret Bowman (Del Rio Motel Clerk), Thomas Kopache (Boot Salesman), Jason Douglas (Cabbie at Motel), Doris Hargrave (Waitress), Rutherford Cravens (Gun Store Clerk), Matthew Posey (Sporting Goods Clerk), George Adelo (Mexican in Bathtub), Mathew Greer (Hitchhiking Driver), Trent Moore (Nervous Accountant), Marc Miles (Hotel Eagle Clerk), Luce Rains (Pickup Driver), Philip Bentham (Border Bridge Youth), Eric Reeves (Border Bridge Youth), Josh Meyer (Border Bridge Youth), Chris Warner (Flatbed Driver), Brandon Smith (INS Official), Roland Uribe (Well Dressed Mexican), Richard Jackson (Chicken Farmer), Josh Blaylock (Boy on Bike) and others.

Roger Deakins (Director of Photography), Roger Deakins (Camera Operator), Nancy Haigh (Set Decoration), Joel Coen (Screenplay), Joel Coen (Editor), Joel Coen (Producer), Ethan Coen (Screenplay) more..., Ethan Coen (Editor), Ethan Coen (Producer), Carter Burwell (Original Music Composer), Ellen Chenoweth (Casting), Scott Rudin (Producer), Jess Gonchor (Production Design), Mark Roybal (Executive Producer), Mary Zophres (Costume Design), Skip Lievsay (Supervising Sound Editor), Skip Lievsay (Sound Re-Recording Mixer), Peter Chesney (Special Effects Coordinator), Craig Berkey (Sound Designer), Craig Berkey (Sound Re-Recording Mixer), Dave Childers (First Company Grip), Bruce Goodman (Colorist), Todd Kasow (Music Editor), Paul Elliott (Second Unit Director of Photography), Robert Graf (Executive Producer), Cormac McCarthy (Novel), David Diliberto (Associate Producer), Jo Edna Boldin (Location Casting), Peter F. Kurland (Sound mixer), Cheryl Kurk (Production Accountant), Thomas Johnston (Script Supervisor), Bruce Hamme (Dolly Grip), Rachel Tenner (Casting Associate), Katie McQuerrey (Assistant Editor), Deborah Jensen (Assistant Art Director), Tracy Kilpatrick (Additional Casting), Jenny Eagan (Assistant Costume Designer), Mamie Mitchell (Script Supervisor), Peter Dress (Second Assistant Director), Roberta Marquez Seret (Art Department Coordinator) and others.