Rebel Wilson (Stephanie Conway), Sam Richardson (Seth Novacelik), Zoë Chao (Tiffany Blanchette-Balbo), Mary Holland (Martha Reiser), Justin Hartley (Blaine Balbo), Chris Parnell (Jim Conway), Angourie Rice (Young Stephanie Conway) more..., Molly Brown (Young Martha Reiser), Zaire Adams (Young Seth Novacelik), Ana Yi Puig (Young Tiffany Blanchette), Tyler Barnhardt (Young Blaine Balboa), Jade Bender (Britney 'Bri Luvs' Balbo), Avantika (Janet), Joshua Colley (Yaz), Jeremy Ray Taylor (Neil Chudd), Michael Cimino (Lance Harrison), Brandon Scott Jones (Mr. T), Tiffany Denise Hobbs (Dr. Jean Johnson), Lauren Halperin (Nurse), Alicia Silverstone (Deanna Russo), Lucy Taylor (Lydia Conway), Merrick McCartha (Principal Young), Ruby Frankel (Drunk Person), Steve Aoki (Steve Aoki), John Crow (News Anchor), Mimi Gould (Movie Goer), Vance Kanell (Usher), Joel Ray Ishman (Chemistry Teacher), Vee Bhakta (Janet's Dad), Leonard R. Butler (Mr. Beenbaum), James Millar (Stoner Student's Dad), Darrell Snedeger (Deanna Russo's Husband), Alyssa Mae Clark (Young Deanna Russo), Grace Chan (Dancer), Jordan Gray Burgess (Preppy Girl)

Chris Bender (Producer), Todd Garner (Producer), David Sandefur (Production Design), Timothy M. Bourne (Producer), David Giammarco (Sound Re-Recording Mixer), Jake Weiner (Executive Producer), Andrew White (Art Direction) more..., Salvador Pérez Jr. (Costume Design), Melanie Hughes (Makeup Department Head), Rebel Wilson (Producer), Rich Delia (Casting), Jermaine Stegall (Original Music Composer), Andrew Knauer (Screenplay), Jeremy Stein (Executive Producer), Arthur Pielli (Screenplay), Sarah Lucky (Editor), Elliott Koretz (Supervising Sound Editor), Yeşim "Shimmy" Osman (Key Hair Stylist), Cheryl Marks (Hair Department Head), Brandon Scott Jones (Screenplay), Noel Hernandez (Makeup Artist), Chris LeDoux (Visual Effects Supervisor), Caleb Hollenback (Sound Recordist), Jake Wagner (Executive Producer), Stephanie Powers (Set Costumer), John Tarro (Hairstylist), Dani Maslaney (Makeup Artist), Randi Owens Arroyo (Makeup Artist), Travis Culberson (Makeup Artist), Antoinette Black (Assistant Hairstylist), Cara Price (Set Decoration), Irenia Vail (Hairstylist), Jessica Craig (Makeup Artist), Jereme Gelske (Visual Effects Producer), Aakomon Jones (Choreographer), Timothy M. Bourne (Unit Production Manager), Andrew Knauer (Story), Arthur Pielli (Story), Marco Fargnoli (Director of Photography), Heath M. Howard (Production Supervisor) and others.