George Clooney (Matt King), Shailene Woodley (Alexandra King), Beau Bridges (Cousin Hugh), Robert Forster (Scott Thorson), Judy Greer (Julie Speer), Matthew Lillard (Brian Speer), Nick Krause (Sid) more..., Amara Miller (Scottie King), Mary Birdsong (Kai Mitchell), Rob Huebel (Mark Mitchell), Patricia Hastie (Elizabeth King), Grace A. Cruz (Scottie's Teacher), Kim Gennaula (School Counselor), Karen Kuioka Hironaga (Barb Higgins), Carmen Kaichi (Lani Higgins), Kaui Hart Hemmings (Matt's Secretary Noe), Matt Corboy (Cousin Ralph), Matt Esecson (Cousin Hal), Michael Ontkean (Cousin Milo), Stanton Johnston (Cousin Stan), Jon McManus (Cousin Six), Hugh Foster (Cousin Wink), Tiare R. Finney (Cousin Connie), Tom McTigue (Cousin Dave), Milt Kogan (Dr. Johnston), Laird Hamilton (Troy Cook), Aileen "Boo" Arnold (Dorm Supervisor), Esther Kang (Alex's Roommate), Melissa Kim (Alex's Drunken Friend), Barbara L. Southern (Alice "Tutu" Thorson), Celia Kenney (Reina), Matt Reese (Buzz), Zoel Turnbull (Hotel Clerk), Linda Rose Herman (Grief Counselor), Scott Michael Morgan (Barry Thorson), Darryl K. Gonzales (Tahiti Nui Singer (Kanak Attack)), Koko Kanealii (Tahiti Nui Singer (Kanak Attack)), Romey "Keola" Yokotake (Tahiti Nui Singer (Kanak Attack)), Fileena Bahris (Passenger (uncredited)), Paul Edney (Bicyclist (uncredited)) and others.

Alexander Payne (Screenplay), Nat Faxon (Screenplay), Jim Rash (Screenplay), Kaui Hart Hemmings (Novel), Jim Burke (Producer), Alexander Payne (Producer), Jim Taylor (Producer) more..., Phedon Papamichael (Director of Photography), Kevin Tent (Editor), John Jackson (Casting), Jane Ann Stewart (Production Design), T.K. Kirkpatrick (Art Direction), Wendy Chuck (Costume Design), George Parra (Co-Producer), Waldo Sanchez (Hair Department Head), Matt Callahan (Set Decoration), Tracy Boyd (Associate Producer), Julie Hewett (Makeup Department Head), Karen Iboshi Preiser (Makeup Artist), Debra Rego (Hairstylist), Jeff Peterson (Original Music Composer),