Meryl Streep (Miranda Priestly), Anne Hathaway (Andy Sachs), Emily Blunt (Emily), Stanley Tucci (Nigel), Kenneth Branagh (Stuart), Justin Theroux (Benji Barnes), Lucy Liu (Sasha Barnes) more..., Tracie Thoms (Lily), Tibor Feldman (Irv Ravitz), B.J. Novak (Jay Ravitz), Patrick Brammall (Peter), Simone Ashley (Amari), Caleb Hearon (Charlie), Helen J. Shen (Jin), Rachel Bloom (Talia), Larry Mitchell (Mack), George C. Wolfe (Paul), Daniel Liu (Dirk), Pauline Chalamet (Ilana), Bria Condon (Marta), Esco Jouléy (Jenny), Rishi Mukherjee (Sandeep), Wes McGee (Frank), Eloise Ro (Bronwyn), Tanya Hutchison (Flight Attendant), Briga Heelan (Passenger), Julia Ty Goldberg (New Second Assistant), Avery Bederman (Nigel's Assistant), Colleen Dengel (Caroline), Suzanne Dengel (Cassidy), Walter Belenky (Awards Announcer), Hillary Carrigan (Airline Announcer), Kendi Nichols (Grace), Elizabeth Lim (Violinist), Devin Moore (Violist), Maureen McDermott (Cellist), Milly Tamarez (Podcaster #1), Catherine Cohen (Podcaster #2), Elizabeth Holder (Gladys), Amanda Morrow (India) and others.

Aline Brosh McKenna (Writer), Wendy Finerman (Producer), Christo Morse (First Assistant Director), Sean Flanigan (Hair Department Head), Nicki Ledermann (Makeup Department Head), Jessica Lichtner (Script Supervisor), Florian Ballhaus (Director of Photography) more..., Theodore Shapiro (Original Music Composer), Ellen Lewis (Casting), Shayna Markowitz (Casting), Stephanie Q. Bowen (Set Decoration), David 'Gus' Gustafson (Production Supervisor), T.J. O'Mara (Sound Mixer), Tracey Ruggiero (Stunt Coordinator), Thomas Lappin ("A" Camera Operator), Katherine Soares (Visual Effects Producer), Tim Van Horn (Visual Effects Supervisor), Jess Gonchor (Production Design), Andrew Marcus (Editor), Molly Rogers (Costume Design), John S. Moyer ("B" Camera Operator), John S. Moyer (Steadicam Operator), Andy Day (Gaffer), Aline Brosh McKenna (Executive Producer), Michael Bederman (Executive Producer), Dani Vitale (Choreographer), Roberto Baez (Makeup Artist), Anastasia Coppola (Hairstylist), Jane DiPersio (Makeup Artist), Etzel Ecleston (Makeup Artist), Sunday Englis (Makeup Artist), Michelle Johnson (Hairstylist), Crystal Jurado (Prosthetic Makeup Artist), Donald McInnes (Hairstylist), Donald McInnes (Makeup Artist), Evelyne Noraz (Makeup Artist), Denna Olivieri (Makeup Artist), Angelo Bonanni (Sound Mixer), Lauren Weisberger (Characters), Karen Rosenfelt (Executive Producer) and others.