Emily Blunt (Margaret Fairchild), Josh O'Connor (Dr. Daniel Kellner), Colin Firth (Noah Scanlon), Eve Hewson (Jane Blakenship), Colman Domingo (Hugo Wakefield), Wyatt Russell (Jackson), Henry Lloyd-Hughes (Casper Boyd) more..., Elizabeth Marvel (Sister Maura), Hettienne Park (Serena), Tommy Martinez (Santiago), Gabby Beans (Angela Childs), Jeremy Shamos (Claypool), Brandon Wilson (Nathan Twining), Priyanka Kedia (Grace Zhao), Lora Lee Gayer (Terri), Lance Hoyt (Red Wrestler), Chavo Guerrero Jr. (Wrestling Referee), Brian Button (Blue Wrestler), Elliot Villar (Agent Diaz), Noah Robbins (Agent Munsey), Brian Hutchison (Wardex Aide), Amir Malaklou (Comm Agent), Jim Parrack (Cop), Clarke Thorell (KCXE Anchor), Elizabeth Stanley (KCXE Anchor), Nina White (KCXE Assistant), Emily Jackson (KCXE Makeup Artist), Margo Seibert (KCXE Floor Manager), Ron Song (Park), David Park (Interpreter), Ephraim Birney (KCXE Teleprompter Tech), Michael Gaston (General Dobbs), Stevie Ray Dallimore (Government Man), Sheetal S. Desai (MRI Technician), Carter Gill (Hospital Wardex Agent), Luke Lesko (Hospital Wardex Agent), Eboni Booth (Dr. Coleman), Robert Engel (Richard Nixon), Bob Greenberg (Jackie Gleason), Aaron Costa Ganis (Cold Room Med Tech) and others.

Kristie Macosko Krieger (Producer), Steven Spielberg (Producer), Steven Spielberg (Story), David Koepp (Screenplay), Adam Stockhausen (Production Design), Rena DeAngelo (Set Decoration), Janusz Kamiński (Director of Photography) more..., Brian Machleit (Stunt Coordinator), Chris Brigham (Executive Producer), Michael Hatzer (Digital Colorist), Cristen Carr Strubbe (Executive In Charge Of Production), Paul Tazewell (Costume Design), Sarah Broshar (Editor), Deborah Jensen (Supervising Art Director), Randy Manion (Unit Production Manager), Cindy Tolan (Casting), Zachary Citarella (Second Assistant Director), Jeremy Marks (First Assistant Director), Josh Muzaffer (Second Unit First Assistant Director), Jessica Lichtner (Script Supervisor), John Williams (Original Music Composer), Drew Kunin (Production Sound Mixer), Judy Chin (Makeup Department Head), Adam Somner (Executive Producer), Matthew E. Butler (Visual Effects Supervisor), Lauren Ritchie (Visual Effects Producer), Lee-Anne Telford (Stunt Double), Becca GT (Stunt Double), Andre Da Silva (Stunt Double), Roy Farfel (Stunt Driver), Derek Johnson (Stunt Double), Joanna Shelmidine (Stunt Double), Mark Pettograsso (Stunts), Quentin Pardee Collins (Stunt Double), Scott Burik (Stunts), Doug Coleman (Stunts), Mike Burke (Stunt Driver), Natalie Diaz (Stunts), Richard Epper (Utility Stunts), Jeremy Fry (Stunts) and others.