Rachel McAdams (Allison "Allie" Hamilton), Ryan Gosling (Noah "Duke" Calhoun), Gena Rowlands (Old Allison "Allie" Hamilton), James Garner (Old Noah "Duke" Calhoun), Sam Shepard (Frank Calhoun), Joan Allen (Anne Hamilton), James Marsden (Lon Hammond Jr.) more..., David Thornton (John Hamilton), Kevin Connolly (Fin), Starletta DuPois (Nurse Esther), Ed Grady (Harry), Jennifer Echols (Nurse Selma), Heather Wahlquist (Sara Tuffington), Jonathan Parks Jordan (Seabrook Boy), Cullen Moss (Bodee), Traci Dinwiddie (Veronica), James Middleton (Aaron), Peter Rosenfeld (Professor), Obba Babatundé (Band Leader), Chuck Pacheco (Bus Driver), Todd Lewis (Reporter), Mark Johnson (Photographer), Robert Fraisse (Buyer #1), Barbara Weetman (Buyer #2), Jamie Anne Allman (Martha Shaw), Rebecca Koon (Aunt Georgia), Deborah Hobart (Aunt Kitty), Sylvia Jefferies (Rosemary), Mark Garner (Lon's Employee), Scott Ritenour (Lon's Employee), Milton Buras (Lon's Employee), Elizabeth Bond (Lon's Secretary), Matthew Barry (Dr. Barnwell), Nancy De Mayo (Mary Allen), David Abrams (Recruit (uncredited)), Taylor Engel (Guy in Movie Theatre (uncredited)), Bob Forrest (Man Having Dinner in Retirement Home (uncredited)), Paul Johansson (Allie's Mom's Ex Boyfriend (uncredited)), Bruce Williamson (Carnival Patron (uncredited)), Renée Amber (Nurse at Counter) and others.

Jeremy Leven (Screenplay), Jan Sardi (Screenplay), Robert Fraisse (Director of Photography), Alan Heim (Editor), Nicholas Sparks (Novel), Avram Butch Kaplan (Executive Producer), Aaron Zigman (Original Music Composer) more..., Mark Johnson (Producer), Rickley W. Dumm (Sound Effects Editor), Claude Letessier (Sound Effects Editor), Jason King (Sound Effects Editor), Brad Sherman (Sound Re-Recording Mixer), Jon Taylor (Sound Re-Recording Mixer), Paul Timothy Carden (Supervising Sound Editor), Kelly Cabral (Supervising Sound Editor), Anthony Cargioli (Boom Operator), Philip Tallman (Music Editor), Sarah Knowles (Production Design), Scott Ritenour (Art Direction), Chuck Potter (Set Decoration), Karyn Wagner (Costume Design), Melinda Taksen (Script Supervisor), Melissa Moseley (Still Photographer), Kristen Donaldson (Art Department Coordinator), Avram Butch Kaplan (Unit Production Manager), Erik Holmberg (Executive In Charge Of Production), Toby Emmerich (Executive Producer), Lynn Harris (Producer), Nancy Green-Keyes (Casting), Matthew Barry (Casting), Milton Buras (Hair Department Head), Linda Grimes (Makeup Department Head), Bob Shelley (Special Effects Coordinator), Cal Johnson (Stunt Coordinator), Lisa Hamil (Casting Associate), Paul Johansson (Thanks), George P. Wilbur (Stunts), Peter J. Silbermann (Unit Publicist), Lori Ayala-Read (Costume Supervisor), Bob Forrest (Thanks) and others.