Matthew McConaughey (Joseph "Coop" Cooper), Jessica Chastain (Murphy "Murph" Cooper), Anne Hathaway (Dr. Amelia Brand), Michael Caine (Professor John Brand), Casey Affleck (Tom Cooper), Mackenzie Foy (Young Murph Cooper), Timothée Chalamet (Young Tom Cooper) more..., Bill Irwin (TARS (voice)), Matt Damon (Dr. Mann), Ellen Burstyn (Old Murph Cooper), John Lithgow (Donald), Wes Bentley (Dr. Doyle), Topher Grace (Getty), David Oyelowo (Principal), David Gyasi (Dr. Romilly), William Devane (NASA Board Member), Josh Stewart (CASE (voice)), Collette Wolfe (Ms. Kelly), Leah Cairns (Lois Cooper), Russ Fega (Crew Chief), Lena Georgas (Nurse Practitioner), Jeff Hephner (Doctor), Elyes Gabel (Administrator), Brooke Smith (Nurse), Liam Dickinson (Coop), Francis X. McCarthy (Boots), Andrew Borba (Smith), Flora Nolan (Girl on Truck), William Patrick Brown (NASA Employee (uncredited)), Cici Leah Campbell (NASA Scientist (uncredited)), Kristian Van der Heyden (Scientist (uncredited)), Mark Casimir Dyniewicz (NASA Inspector (uncredited)), Joseph Oliveira (Astronaut (uncredited)), Ryan Irving (Popcorn Seller (uncredited)), Alexander Michael Helisek (Construction Boss (uncredited)), Benjamin Hardy (NASA Scientist (uncredited)), Griffen Fraser (Boy on Truck)

Kendelle Elliott (Art Direction), Eggert Ketilsson (Art Direction), David F. Klassen (Art Direction), Gary Kosko (Art Direction), Josh Lusby (Art Direction), Eric Sundahl (Art Direction), Lee Smith (Editor) more..., Lynda Obst (Producer), Christopher Nolan (Producer), Hoyte van Hoytema (Director of Photography), Hans Zimmer (Original Music Composer), Jonathan Nolan (Writer), Christopher Nolan (Writer), Nathan Crowley (Production Design), Mary Zophres (Costume Design), Emma Thomas (Producer), John Papsidera (Casting), Gary Fettis (Set Decoration), Patricia DeHaney (Hairstylist), Jose Zamora (Hairstylist), Luisa Abel (Makeup Department Head), Jay Wejebe (Makeup Artist), Casey Grant (Production Manager), Michelle Brattson (Production Supervisor), Jenne Lee (Art Department Coordinator), Lynda Foote (Costume Supervisor), Heather Moore (Costume Supervisor), P. Scott Sakamoto (Camera Operator), Hans Bjerno (Helicopter Camera), Melinda Sue Gordon (Still Photographer), Dane Bjerno (Camera Technician), Jordan Goldberg (Executive Producer), Jake Myers (Executive Producer), Kip Thorne (Executive Producer), Thomas Tull (Executive Producer), Joel Tobman (Art Department Coordinator), Lauren Abiouness (Assistant Art Director), Travis Witkowski (Assistant Art Director), Craig Henderson (Construction Coordinator), Brian Walker (Construction Coordinator) and others.