Hugh Grant (Samuel Faulkner), Julianne Moore (Rebecca Taylor), Tom Arnold (Marty Dwyer), Joan Cusack (Gail Dwyer), Jeff Goldblum (Sean Fletcher), Robin Williams (Dr. Kosevich), Mia Cottet (Lili) more..., Joey Simmrin (Truman), Ashley Johnson (Shannon Dwyer), Alexa PenaVega (Molly Dwyer), Aislin Roche (Patsy Dwyer), Priscilla Alden (Older Woman), Edward Ivory (Older Man), James Brady (Bicyclist), Charles Martinet (Arnie), Emily Yancy (Dr. Thatcher), Kristin Davis (Tennis Attendant), Betsy Monroe (Bobbie), Eleanor Columbus (Little Girl #1 in Ballet Class), Anna Barnathan (Little Girl #2 in Ballet Class), Zelda Williams (Little Girl #3 in Ballet Class), Cheryl Lee Thorup (Christine), Violet Columbus (Baby in Toy Store), Irene Columbus (Woman in Toy Store), Betsy Aidem (Gail's Nurse), Terence McGovern (Dr. Newsoe, the Anesthesiologist), Maureen McVerry (Pregnant Woman #1), Velina Brown (Pregnant Woman #2), Joy M. Cook (Pregnant Woman #3), Sue Murphy (Pregnant Woman #4), Gwen Holloway (Female Delivery Room Nurse), Diane Amos (Rebecca's Nurse), Geoff Bolt (Male Delivery Room Nurse), Bruce Devan (Doctor in Hallway), Tim Moffett (Sean's Friend #3), Clarke Devereux (Emergency Attendant #1)

Chris Columbus (Screenplay), Chris Columbus (Producer), Michael Barnathan (Producer), Anne François (Producer), Mark Radcliffe (Producer), Hans Zimmer (Original Music Composer), Donald McAlpine (Director of Photography) more..., Raja Gosnell (Editor), Stephen E. Rivkin (Editor), Carol DePasquale (Script Supervisor), Mary Duann (Production Coordinator), Janet Hirshenson (Casting), Jane Jenkins (Casting), Angelo P. Graham (Production Design), Jay Hurley (Costume Design), Garrett Lewis (Set Decoration), W. Steven Graham (Art Direction), Alexandra Fitzpatrick (Art Department Coordinator), Phil Bray (Still Photographer), David Luckenbach (Steadicam Operator), Steven R. Mathis (Gaffer), Robert Shoup (Supervising Sound Editor), Lora Hirschberg (Sound Re-Recording Mixer), Tom Johnson (Sound Re-Recording Mixer), Randy Thom (Sound Designer), Ethan van der Ryn (Sound Effects Editor), Glenn R. Wilder (Stunt Coordinator), John McLeod (Special Effects Coordinator), Jacqueline A. Shea (Production Supervisor), Joan Bradshaw (Executive Producer), Christopher Lambert (Executive Producer), Adam Milo Smalley (Music Editor), Rolf Johnson (Music Editor), Kevin D. Ross (First Assistant Editor), Joan Bradshaw (Unit Production Manager), Paula DuPré Pesmen (Associate Producer), Sara Bolder (Dialogue Editor), Michael Silvers (Dialogue Editor), Clare C. Freeman (Dialogue Editor), Nelson Stoll (Sound Mixer) and others.