Dustin Hoffman (Raymond Babbitt), Tom Cruise (Charlie Babbitt), Valeria Golino (Susanna), Gerald R. Molen (Dr. Bruner), Jack Murdock (John Mooney), Michael D. Roberts (Vern), Ralph Seymour (Lenny) more..., Lucinda Jenney (Iris), Bonnie Hunt (Sally Dibbs), Kim Robillard (Township Doctor), Beth Grant (Mother at Farm House), Dolan Dougherty (Farm Kid#1), Marshall Dougherty (Farm Kid#2), Patrick Dougherty (Farm Kid#3), Peter Dougherty (Farm Kid#5), Andrew Dougherty (Farm Kid#6), Loretta Wendt Jolivette (Secretary Dr. Bruner), Donald E. Jones (Minister at Funeral), Bryon P. Caunar (Patient in Waiting Room), Donna J. Dickson (Nurse), Ralph Tabakin (Shift Boss), Ray Baker (Mr. Kelso), Jake Hoffman (Boy at Pancake Counter), Royce D. Applegate ((voice)), Anna Mathias ((voice)), Archie Hahn ((voice)), Luisa Leschin ((voice)), Ira Miller ((voice)), Chris Mulkey ((voice)), Julie Payne ((voice)), Reni Santoni ((voice)), Ruth Silveira ((voice)), Jonathan Stark ((voice)), Lynne Marie Stewart ((voice)), Arnold F. Turner ((voice)), Gigi Vorgan ((voice)), Barry Levinson (Doctor (uncredited)), Mark Winn (Restaurant Patron (uncredited)), June Christopher ((voice)), Billie Perkins (Hotel Customer (uncredited))

Ronald Bass (Screenplay), Mark Johnson (Producer), Peter Guber (Executive Producer), Jon Peters (Executive Producer), Hans Zimmer (Original Music Composer), John Seale (Director of Photography), Stu Linder (Editor) more..., Louis DiGiaimo (Casting), Barry Morrow (Screenplay), Gerald R. Molen (Co-Producer), Pieter Hubbard (Sound Editor), Richard Bryce Goodman (Sound Mixer), Ida Random (Production Design), William A. Elliott (Art Direction), Bernie Pollack (Costume Design), Richard Beggs (Sound Designer), Linda DeScenna (Set Decoration), Edwin Butterworth (Makeup Artist), Donald Myers (Special Effects), Marshall Schlom (Script Supervisor), Stephen Vaughan (Still Photographer), Barry Morrow (Story), Gerald R. Molen (Unit Production Manager), David McGiffert (Associate Producer), Gail Mutrux (Associate Producer), Mel Metcalfe (Sound Re-Recording Mixer), David J. Hudson (Sound Re-Recording Mixer), Terry Porter (Sound Re-Recording Mixer), Hal Sanders (Sound Editor), Bill Phillips (Supervising Sound Editor), Bruce Lacey (Sound Editor), Jimmy Ling (Sound Editor), Jeffrey Wilhoit (Sound Editor), John A. Larsen (Sound Editor), M. Todd Henry (Camera Operator), Kenneth Zunder (Camera Operator), Blair Daily (Assistant Editor), James Flamberg (Music Editor), Allan Mason (Music Supervisor), Robin Citrin (Location Manager) and others.