Rowan Atkinson (Johnny English), Daniel Kaluuya (Colin Tucker), Dominic West (Simon Ambrose), Rosamund Pike (Kate Sumner), Gillian Anderson (Pamela Thornton ("Pegasus")), Tim McInnerny (Patch Quartermain), Pik-Sen Lim (Killer Cleaner) more..., Togo Igawa (Ting Wang), Burn Gorman (Slater), Stephen Campbell Moore (Prime Minister), Richard Schiff (Titus Fisher), Mariella Frostrup (Royce (Voice)), Rupert Vansittart (Derek), Isla Blair (Shirley), Emma Vansittart (Margaret), Eric Carte (Agent One), Roger Barclay (Agent Two), Christina Chong (Barbara), Miles Jupp (Technician), Ellen Thomas (Tucker's Mum), Benedict Wong (Chi Han Ly), Lobo Chan (Xiang Ping), Mark Ivanir (Karlenko), Isabella Blake-Thomas (Izzie), Andrew Woodall (Foreign Secretary), Chris Jarman (Michael Tembe), Wale Ojo (President Chambal), Joséphine de la Baume (Madeleine), Eleanor Wyld (Receptionist), Margaret Clunie (Receptionist), Mandi Sidhu (Receptionist), Clara Paget (Waitress), Richard Syms (Man in Pinstripe), Marvin Beyster ((uncredited))

William Davies (Writer), Jim Clay (Production Design), Stephen McLaughlin (Music Score Producer), Stephen McLaughlin (Scoring Mixer), Beatrix Aruna Pasztor (Costume Designer), Tim Bevan (Producer), Eric Fellner (Producer) more..., Debra Hayward (Executive Producer), Liza Chasin (Executive Producer), Hamish McColl (Screenplay), Ronaldo Vasconcellos (Co-Producer), William Davies (Executive Producer), Lucy Bevan (Casting), Ilan Eshkeri (Music), Danny Cohen (Director of Photography), Guy Bensley (Editor), Nick Angel (Music Supervisor), Chris Clark (Producer), Graham Johnston (Makeup & Hair),