Nicolas Cage (Seth), Meg Ryan (Maggie Rice), Andre Braugher (Cassiel), Dennis Franz (Nathaniel Messinger), Colm Feore (Jordan), Robin Bartlett (Anne), Joanna Merlin (Teresa Messinger) more..., Sarah Dampf (Susan), Rhonda Dotson (Susan's Mother), Nigel Gibbs (Doctor), John Putch (Man in Car), Lauri Johnson (Woman in Car), Christian Aubert (Foreign Visitor in Car), Jay Patterson (Air Traffic Controller), Shishir Kurup (Jimmy, Anesthesiologist), Brian Markinson (Tom, Surgical Fellow), Elisabeth Shue (Pregnant Woman), Alexander Gould (Little Boy (Uncredited)), Kiều Chinh (Asian Woman), Nick Offerman (Construction Worker)

Wim Wenders (Screenplay), Peter Handke (Author), Richard Reitinger (Screenplay), Dana Stevens (Screenplay), Charles Roven (Producer), Dawn Steel (Producer), Gabriel Yared (Original Music Composer) more..., John Seale (Director of Photography), Lynzee Klingman (Editor), Mark A. Mangini (Supervising Sound Editor), Ronna Kress (Casting Associate), Robert Cavallo (Executive Producer), Arnon Milchan (Executive Producer), Vince Deadrick Jr. (Stunts), Lilly Kilvert (Production Design), John Warnke (Art Direction), Gretchen Rau (Set Decoration), Jess Gonchor (Construction Foreman), Gabriel Yared (Orchestrator), David Rubin (Casting), Ellen Heuer (Foley Artist), Marilyn Graf (Foley Mixer), Rick Seaman (Stunts), Jeff Levine (Associate Producer), Alan Glazer (Associate Producer), Ezra Dweck (Foley Editor), Charles Newirth (Executive Producer), Keith Campbell (Stunts), Shay Cunliffe (Costume Design), Adam Boome (Associate Editor), Dianne Wager (Assistant Art Director), Joe Bucaro III (Stunts), Allegra Clegg (Unit Production Manager), Kelley Smith-Wait (Co-Producer), Thomas Rosales Jr. (Stunts), Patrick Cassidy (Leadman), Michele Panelli-Venetis (First Assistant Director), Matt Rebenkoff (Second Assistant Director), Morris Flam (Chief Lighting Technician), Jason Rodriguez (Stunts) and others.