Tom Cruise (Lestat), Brad Pitt (Louis), Antonio Banderas (Armand), Christian Slater (Malloy), Stephen Rea (Santiago), Kirsten Dunst (Claudia), Domiziana Giordano (Madeleine) more..., Thandiwe Newton (Yvette), Laure Marsac (Mortal Woman on Stage), John McConnell (Gambler), Mike Seelig (Pimp), Bellina Logan (Tavern Girl), Lyla Hay Owen (Widow St. Clair), Lee E. Scharfstein (Widow's Lover), Monte Montague (Plague Victim Bearer), Nathalie Bloch (Maid), Jeanette Kontomitras (Woman in Square), Roger Lloyd Pack (Piano Teacher), George Kelly (Dollmaker), Nicole DuBois Favre (Creole Woman), Virginia McCollam (Whore on Waterfront), Helen McCrory (2nd Whore), Indra Ové (New Orleans Whore), Micha Bergese (Paris Vampire), Rory Edwards (Paris Vampire), Marcel Iureș (Paris Vampire), Susan Lynch (Paris Vampire), Louise Kim Salter (Paris Vampire), Matthew Sim (Paris Vampire), François Testory (Paris Vampire), Andrew Tiernan (Paris Vampire), Simon Tyrrell (Paris Vampire), George Antoni (Paris Vampire), Sara Stockbridge (Estelle), Katia Caballero (Woman in Audience), Louis Lewis-Smith (Mortal Boy)

Anne Rice (Screenplay), David Geffen (Producer), Stephen Woolley (Producer), Elliot Goldenthal (Original Music Composer), Philippe Rousselot (Director of Photography), Mick Audsley (Editor), Joke van Wijk (Editor) more..., Susie Figgis (Casting), Juliet Taylor (Casting), Dante Ferretti (Production Design), Francesca Lo Schiavo (Set Decoration), Sandy Powell (Costume Design), Sandrine Ageorges (Unit Production Manager), Ansel M. Stroud Jr. (Thanks), Redmond Morris (Co-Producer), Stephen McLaughlin (Scoring Mixer), Matthias Gohl (Music Score Producer), River Phoenix (In Memory Of), Anne Rice (Novel), Gary Archer (Prosthetics), Philip Kohler (Unit Production Manager), Joe Burns (Second Assistant Director), Chris Brigham (Unit Production Manager), Stan Winston (Makeup Effects Designer), Robert Legato (Visual Effects Supervisor), Robert Legato (Second Unit Director), Jean-Pierre Avice (Unit Production Manager), John Engel (Unit Production Manager), Patrick Clayton (First Assistant Director), Michael Stevenson (Second Assistant Director), George Fenton (Music Supervisor), Nick Gillard (Stunts), Ken Court (Assistant Art Director), Stella Vaccaro (Set Designer), Jean-Michel Ducourty (Assistant Art Director), Malcolm Middleton (Supervising Art Director), James E. Tocci (Art Direction), Greg Powell (Stunt Coordinator), Nick Dudman (Makeup Artist), Nick Dudman (Key Makeup Artist) and others.