James McAvoy (Patricia / Dennis / Hedwig / The Beast / Barry / Heinrich / Jade / Ian / Mary Reynolds / Norma / Jalin / Kat / B.T. / Kevin Wendell Crumb / Mr. Pritchard / Felida / Luke / Goddard / Samuel / Polly), Bruce Willis (David Dunn / The Overseer), Samuel L. Jackson (Elijah Price / Mr. Glass), Sarah Paulson (Dr. Ellie Staple), Anya Taylor-Joy (Casey Cooke), Spencer Treat Clark (Joseph Dunn), Charlayne Woodard (Mrs. Price) more..., Luke Kirby (Pierce), Adam David Thompson (Daryl), M. Night Shyamalan (Jai, Security Guard), Shannon Destiny Ryan (Cheerleading Girl), Diana Silvers (Cheerleading Girl), Nina Wisner (Cheerleading Girl), Kyli Zion (Cheerleading Girl), Serge Didenko (Ronald, Powerful Young Man), Russell Posner (T, Skinny Camera Kid), Kimberly S. Fairbanks (Assistant Principal), Rosemary Howard (Penelope Crumb), Bryan McElroy (Clarence Crumb), Owen Vitullo (Young Kevin), William Turner (Young Elijah), Johnny Hiram Jamison (Thirteen Year-Old Elijah (archive footage)), Leslie Stefanson (Woman on Train), Marc H. Glick (Train Engineer), Brick Mason (Carnival Barker), Bostin Christopher (Comic Book Counter Guy), Ukee Washington (News Anchor), Colin Becker (Ten Year-Old David), Brian Anthony Wilson (Security Guard in Car), Tobias Segal (Surveillance Security Guard), Joseph Thuet (Joe, Security Guard), Tatiana St. Phard (Woman Group Member), Tom DiNardo (Homeless Person), Timothy Chivalette (Comic Book Geek), Jack McCafferty (Comic Book Geek), Darby Schlosser (Foster Sibling), Jordan Coker (Foster Sibling), Emma Hong (Foster Sibling), Xaiver Gerald (Foster Sibling), Tim Duquette (Patient Jimmy) and others.

Jason Blum (Producer), Chris Trujillo (Production Design), Luke Ciarrocchi (Editor), Mike Gioulakis (Director of Photography), Marc Bienstock (Producer), Kevin Scott Frakes (Executive Producer), Ashwin Rajan (Producer) more..., John Rusk (Co-Producer), Steven Schneider (Executive Producer), M. Night Shyamalan (Producer), Renaldo Kell (Editor), Douglas Aibel (Casting), Jesse Rosenthal (Art Direction), Olivia Peebles (Set Decoration), Paco Delgado (Costume Design), Ben Bornstein (Prosthetic Makeup Artist), Margina Dennis (Makeup Artist), Diane Dixon (Hair Department Head), Michael Maddi (Prosthetic Designer), Michael Maddi (Prosthetics Sculptor), Pamela Peitzman (Makeup Department Head), John Burton West (Production Manager), West Dylan Thordson (Original Music Composer), M. Night Shyamalan (Screenplay), Jason Fyrberg (Sound Mixer), William Lance (Set Designer), Sean Garnhart (Sound Designer), Dave Kellom (Art Department Coordinator), Paul Maiello (Construction Coordinator), Tim Linden (Property Master), Aaron Becker (Title Designer), Yusuf Hassan (Script Coordinator), Charles S. Rowe (Script Supervisor), Dann Fink (ADR Voice Casting), Diane Heery (Casting), Jason Loftus (Casting), Thomas Devine (Electrician), Andrew Joffe (Electrician), Jon Sibert (Key Grip), Ryan 'Sparks' Lynch (Chief Lighting Technician) and others.