Tom Cruise (Ethan Hunt), Philip Seymour Hoffman (Owen Davian), Ving Rhames (Luther Stickell), Billy Crudup (John Musgrave), Michelle Monaghan (Julia Meade), Jonathan Rhys Meyers (Declan Gormley), Keri Russell (Lindsey Farris) more..., Maggie Q (Zhen Lei), Laurence Fishburne (Theodore Brassel), Simon Pegg (Benjamin "Benji" Dunn), Eddie Marsan (Brownway), Bahar Soomekh (Davian's Translator), Jeff Chase (Davian's Bodyguard), Michael Berry Jr. (Julia's Kidnapper), Aaron Paul (Rick Meade), Carla Gallo (Beth), Bellamy Young (Rachael), Paul Keeley (Ken), Jane Daly (Julia's Mother), Greg Grunberg (Kevin), Sabra Williams (Annie), Rose Rollins (Ellie), Sasha Alexander (Melissa), Tracy Middendorf (Ashley)

Bruce Geller (Original Story), Tom Cruise (Producer), Paula Wagner (Producer), Michael Giacchino (Original Music Composer), Dan Mindel (Director of Photography), Maryann Brandon (Editor), Mary Jo Markey (Editor) more..., April Webster (Casting), Scott Chambliss (Production Design), Dennis Bradford (Art Direction), Karen Manthey (Set Decoration), Colleen Atwood (Costume Design), Michèle Burke (Makeup Artist), Warren Hanneman (Hairstylist), Stephen M. Davis (Music Editor), Mark P. Stoeckinger (Supervising Sound Editor), Daniel Acon (Special Effects Coordinator), Daniel Sudick (Special Effects), Nina Fallon (Visual Effects), Vic Armstrong (Stunt Coordinator), Wade Allen (Stunts), Alex Kurtzman (Writer), Roberto Orci (Writer), J.J. Abrams (Writer), Tyler Allison (Camera Department Manager), Sebastian Milito (Construction Coordinator), Brad Ricker (Art Direction),