Cate Blanchett (Elizabeth I), Joseph Fiennes (Robert Dudley, Earl of Leicester), Geoffrey Rush (Sir Francis Walsingham), Christopher Eccleston (Duke of Norfolk), John Gielgud (The Pope), Richard Attenborough (Sir William Cecil) more..., Fanny Ardant (Mary of Guise), Eric Cantona (Monsieur de Foix), Vincent Cassel (Duc d'Anjou), Kathy Burke (Queen Mary Tudor), Edward Hardwicke (Earl of Arundel), Emily Mortimer (Kat Ashley), James Frain (Alvaro de la Quadra), Kelly Macdonald (Isabel Knollys), Kenny Doughty (Sir Thomas Elyot), Daniel Craig (John Ballard), Alfie Allen (Arundel's Son), Jamie Foreman (Earl of Sussex), Lily Allen (Lady in Waiting), Amanda Ryan (Lettice Howard), Sally Grey (Lady in Waiting), Elika Gibbs (Lady in Waiting), Sarah Owen (Lady in Waiting), Kate Loustau (Lady in Waiting), Daniel Moynihan (First Bishop), Jeremy Hawk (Second Bishop), Daisy Bevan (Arundel's Daughter), Hayley Burroughs (Lady in Waiting), Joe White (Master of the Tower), Liam Foley (Norfolk's Man), Matt Andrews (Norfolk's Man), Ben Frain (Young French Man), Lewis Jones (Priest), Michael Beint (Bishop Carlisle), Angus Deayton (Waad, Chancellor of the Eschequer), Joseph O'Conor (Earl of Derby), Brendan O'Hea (Lord William Howard), Edward Highmore (Lord Harewood), James Rowe (Bishop (in Cellar)), Donald Pelmear (Third Bishop) and others.

Michael Hirst (Screenplay), Tim Bevan (Producer), Eric Fellner (Producer), Alison Owen (Producer), David Hirschfelder (Original Music Composer), Remi Adefarasin (Director of Photography), Jill Bilcock (Editor) more..., John Myhre (Production Design), Simone Ireland (Casting), Vanessa Pereira (Casting), Lucy Richardson (Art Direction), Alexandra Byrne (Costume Design), Christine Whitney (Hairstylist), Ivana Primorac (Makeup Artist), Christine Whitney (Makeup Artist), Fred Evans (Sculptor), Roy Rodgers (Sculptor), Brian Bishop (Scenic Artist), Matthew Gray (Set Designer), Terry Forrestal (Stunt Coordinator), Philip Sindall (Camera Operator), Ivana Primorac (Hairstylist), Miranda Davidson (Hairstylist), Karen Ferguson (Hairstylist), Anita Burger (Hairstylist), Christine Greenwood (Hairstylist), Nicola Barnes (Art Department Coordinator), Poppy Luard (Assistant Art Director), Mark Auguste (Supervising Sound Editor), Mike Dowson (Sound Re-Recording Mixer), Mark Taylor (Sound Re-Recording Mixer), George Gibbs (Special Effects Coordinator), Peter Chiang (Visual Effects Supervisor), Sean Savage (Camera Operator), Jimmy Wilson (Gaffer), Kate Buckland (First Assistant Editor), Andrew MacRitchie (First Assistant Editor), Michael Higham (Music Editor), Dave Machin (Transportation Coordinator), Pat Rambaut (Script Supervisor) and others.