Bill Murray (Chief Cliff Robertson), Adam Driver (Officer Ronnie Peterson), Tilda Swinton (Zelda Winston), Chloë Sevigny (Officer Mindy Morrison), Steve Buscemi (Farmer Frank Miller), Danny Glover (Hank Thompson), Caleb Landry Jones (Bobby Wiggins) more..., Selena Gomez (Zoe), Austin Butler (Jack), Luka Sabbat (Zach), Rosie Perez (Posie Juarez), Eszter Balint (Fern), Iggy Pop (Male Coffee Zombie), Sara Driver (Female Coffee Zombie), RZA (Dean), Carol Kane (Mallory O'Brien), Larry Fessenden (Danny Perkins), Rosal Colon (Lily), Sturgill Simpson (Guitar Zombie), Jodie Markell (Woman on TV), Charlotte Kemp Muhl (Fashion Zombie), Maya Delmont (Stella), Taliyah Whitaker (Olivia), Jahi Di'Allo Winston (Geronimo), Tom Waits (Hermit Bob), Kevin McCormick (Guard One), Sid O'Connell (Guard Two), Norman Aaronson (Elderly Diner Patron (uncredited)), Alyssa Maria App (Kid Zombie (uncredited)), Monica Ayres (Cable Zombie (uncredited)), Lorenzo Beronilla (Zelda Zombie (uncredited)), Justin Clarke (Cemetery Zombie (uncredited)), Mick Coleman (Zombie (uncredited)), Vin Craig (Diner Patron (uncredited)), Joseph Anthony Davis (Police Station Zombie (uncredited)), Kimberly Michelle Doherty (Zombie (uncredited)), Austin Ferris (Zombie (uncredited)), Brad Groux (Zombie (uncredited)), Lexa Hayes (Zombie (uncredited)), David Hilfstein (Hardware Zombie / Golf Zombie (uncredited)) and others.

Jim Jarmusch (Writer), Carter Logan (Producer), Joshua Astrachan (Producer), Alex DiGerlando (Production Design), Kendall Anderson (Set Decoration), Catherine George (Costume Design), Affonso Gonçalves (Editor) more..., Arielle De Saint Phalle (Associate Producer), Marcelo Gandola (Co-Executive Producer), Fredrik Zander (Co-Executive Producer), Peter Possne (Head of Production), Ellen Lewis (Casting), Crist Ballas (Prosthetic Makeup Artist), Crystal Jurado (Special Effects Makeup Artist), Valeria Kole (Special Effects Makeup Artist), Michael Marino (Prosthetic Designer), Gary Martori (Key Hair Stylist), Rich Krusell (Special Effects Makeup Artist), Christalla Philippou (Special Effects Makeup Artist), Greg Pikulski (Prosthetic Makeup Artist), Brett Schmidt (Prosthetic Makeup Artist), Alex Hansson (Visual Effects Supervisor), Robert Fernandez (Sound Re-Recording Mixer), Robert Hein (Sound Re-Recording Mixer), Drew Kunin (Sound Mixer), Grant Elder (Sound Effects Editor), Sunny Edelman (Extras Casting Assistant), Frederick Elmes (Director of Photography), Judy Chin (Makeup Department Head), Glenfield Payne (Sound Effects Editor), Julia Heymans (Art Direction), Tom Molinelli (Makeup Artist), Nathan Meier (Visual Effects), Jason Tsang (Visual Effects), Petter Lindholm (Visual Effects), Eileen Sieff Stroup (Set Costumer), Sarah Dano (Set Costumer), Shane Claire Strano (Set Dresser), Brandon Boyles (Set Dresser), George Couri (Set Dresser) and others.