Dwayne Johnson (Dr. Smolder Bravestone), Jack Black (Professor Sheldon 'Shelly' Oberon), Kevin Hart (Franklin 'Mouse' Finbar), Karen Gillan (Ruby Roundhouse), Awkwafina (Ming), Nick Jonas (Jefferson 'Seaplane' McDonough), Alex Wolff (Spencer Gilpin) more..., Ser'Darius Blain (Anthony 'Fridge' Johnson), Morgan Turner (Martha Kaply), Madison Iseman (Bethany), Danny DeVito (Eddie), Danny Glover (Milo), Colin Hanks (Alex), Rhys Darby (Nigel Billingsley), Dania Ramirez (Lady in Red), Darin Ferraro (The Gun Seller), Sal Longobardo (Tony), Massi Furlan (Switchblade), Michael Beasley (Coach Davis), Charles Green (Bartender), Shiquita James (Pedestrian), James William Ballard (Bad Guy in Fortress), Marque Hernandez (Gypsy Guy in Tattoo Chair), Kodai Yamaguchi (Jumanjian Villager), Ashley Scott (Ashley), Rory McCann (Jurgen the Brutal), Bebe Neuwirth (Nora), Lamorne Morris (Heater Repair Guy), John Ross Bowie (Cavendish), Lucy DeVito (Maiden), Marin Hinkle (Spencer's Mom), Melissa Kennemore (Marauder 1 / Jergens Inner Circle)

Scott Rosenberg (Writer), Jeff Pinkner (Writer), Matt Tolmach (Producer), Dany Garcia (Producer), Hiram Garcia (Producer), Dwayne Johnson (Producer), Bill Brzeski (Production Design) more..., Kevin Kersting (Grip), Mike Weber (Executive Producer), Ted Field (Executive Producer), Andrew Max Cahn (Supervising Art Director), Mark Breakspear (Visual Effects Supervisor), Steve Edwards (Editor), Jake Kasdan (Producer), David B. Householter (Executive Producer), Melvin Mar (Executive Producer), Scott Rosenberg (Executive Producer), Jeff Pinkner (Executive Producer), William Teitler (Executive Producer), Chris van Allsburg (Executive Producer), Jake Kasdan (Writer), Henry Jackman (Original Music Composer), Gyula Pados (Director of Photography), Nicole Abellera (Casting Director), Jeanne McCarthy (Casting Director), Michael Gowen (Art Direction), Drew Monahan (Art Direction), Brian Stultz (Art Direction), Stella Vaccaro (Art Direction), Danielle Berman (Set Decoration), Louise Mingenbach (Costume Design),