Tom Hanks (Paul Edgecomb), David Morse (Brutus "Brutal" Howell), Bonnie Hunt (Jan Edgecomb), Michael Clarke Duncan (John Coffey), James Cromwell (Warden Hal Moores), Michael Jeter (Eduard Delacroix), Graham Greene (Arlen Bitterbuck) more..., Doug Hutchison (Percy Wetmore), Sam Rockwell ('Wild Bill' Wharton), Barry Pepper (Dean Stanton), Jeffrey DeMunn (Harry Terwilliger), Patricia Clarkson (Melinda Moores), Harry Dean Stanton (Toot-Toot), Dabbs Greer (Old Paul Edgecomb), Eve Brent (Elaine Connelly), William Sadler (Klaus Detterick), Mack Miles (Orderly Hector), Rai Tasco (Man in Nursing Home), Paula Malcomson (Marjorie Detterick), Christopher Joel Ives (Howie Detterick), Evanne Drucker (Kathe Detterick), Bailey Drucker (Cora Detterick), Brian Libby (Sheriff McGee), Brent Briscoe (Bill Dodge), Bill McKinney (Jack Van Hay), Gary Sinise (Lawyer Burt Hammersmith), Rachel Singer (Cynthia Hammersmith), Scotty Leavenworth (Hammersmith's Son), Bill Gratton (Earl the Plumber), Dee Croxton (Woman at Del's Execution), Rebecca Klingler (Wife at Del's Execution), Gary Imhoff (Husband at Del's Execution), Van Epperson (Police Officer), David E. Browning (Reverend at Funeral), Tommy Barnes (Tower Guard (uncredited)), Wes Hall (Prisoner (uncredited)), Phil Hawn (Police Photographer (uncredited)), Judy Herrera (Bitterbuck's Daughter (uncredited)), Ted Hollis (Coffee Execution Witness (uncredited)), Gower Mills (Inmate (uncredited)) and others.

Frank Darabont (Screenplay), David Valdes (Producer), Frank Darabont (Producer), Thomas Newman (Original Music Composer), David Tattersall (Director of Photography), Richard Francis-Bruce (Editor), Mali Finn (Casting) more..., Terence Marsh (Production Design), Michael Seirton (Set Decoration), Karyn Wagner (Costume Design), Stephen King (Novel), Ralph Nelson Jr. (Still Photographer), Fred Fein (Stand In), Jessica Drake (Dialect Coach), Craig Barron (Visual Effects Supervisor), Janis Clark (Hairstylist), Marsha Bozeman (Set Costumer), Kerry Rossall (Stunts), Robert C. Lusted (First Assistant Editor), Daniel C. Striepeke (Makeup Artist), Deborah La Mia Denaver (Makeup Artist), Andrew Dickler (Assistant Editor), Susan Malerstein (Script Supervisor), Nina Paskowitz (Key Hair Stylist), William Cruse (Supervising Art Director), David Emmerichs (Steadicam Operator), David Emmerichs (Camera Operator), Bobby Burton (Gaffer), Jimmy Keys (Rigging Gaffer), L. Dean Jones Jr. (Unit Production Manager), Beatriz Kerti (Art Department Coordinator), Willie D. Burton (Sound Mixer), Elliot Tyson (Sound Re-Recording Mixer), Michael Herbick (Sound Re-Recording Mixer), Robert J. Litt (Sound Re-Recording Mixer), Mark A. Mangini (Supervising Sound Editor), Marvin E. Lewis (Boom Operator), Bill Bernstein (Music Editor), Carrie Durose (Production Coordinator), Alan B. Curtiss (Assistant Director) and others.